MEDICAL PHYSIOLOGY

PHYSIOLOGY

CENTRAL NERVOUS SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What type of cell is part of the blood brain barrier
A
astrocytes
B
schwann
C
satellite
D
oligodendrocytes
Explanation: 

Detailed explanation-1: -Astrocytes are a major glial cell type, which extend polarized cellular processes that ensheath either neuronal processes or blood vessels (Abbott et al.

Detailed explanation-2: -The BBB is composed by brain capillary endothelial cells (ECs), with a specific phenotype located in a strong association with astrocytic endfeet processes and mesenchymal-like cells pericytes.

Detailed explanation-3: -Astrocytes are an essential part of the BBB in modulating and maintaining the barrier properties of the brain endothelial cells (BECs).

Detailed explanation-4: -The BBB is formed by endothelial cells (ECs), surrounded by an endothelial and astroglial basement membranes with pericytes embedded in between. These are surrounded by astrocyte endfeet that provide support to endothelial function and establish communication with neurons.

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