PHYSIOLOGY
CENTRAL NERVOUS SYSTEM
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
Which of the following substances is least able to cross the blood-brain barrier?
|
|
Water
|
|
|
Sodium ions
|
|
|
Glucose
|
|
|
White blood cells
|
Explanation:
Detailed explanation-1: -Hydrophilic substances, for example, hydron and bicarbonate, are not permitted to pass through cells and across the blood-brain barrier.
Detailed explanation-2: -Most biologic drugs, e.g., recombinant proteins, therapeutic antibodies, or nucleic acid drugs, are large molecule drugs that do not cross the BBB.
Detailed explanation-3: -Cells (such as platelets, white blood cells, and red blood cells), pathogens (such as bacteria), antibiotics, and proteins do not pass the blood-brain barrier at all under normal conditions.
There is 1 question to complete.