PHYSIOLOGY
ENDOCRINOLOGY
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Question
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Process wherein tyrosine residues are iodinated by iodine
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Organification
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Iodide trapping
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Deiodinization
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Iodinizarion
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Explanation:
Detailed explanation-1: -Iodination of tyrosine residues in thyroglobulin is a key step in thyroid hormone biosynthesis. In one sense, therefore, it is not surprising that excess iodine can lead to increased thyroid hormone production. However, there are mechanisms to control thyroid hormone overproduction in these situations.
Detailed explanation-2: -Organification: TPO links tyrosine residues of thyroglobulin protein with I2. It generates monoiodotyrosine (MIT) and diiodotyrosine (DIT).
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