MEDICAL PHYSIOLOGY

PHYSIOLOGY

ENDOCRINOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The major constituent of colloid is the large glycoprotein called ____
A
Thyroglobulin
B
Albumin
C
Thyroxine binding globulin
D
Thyrpoeroxidase
Explanation: 

Detailed explanation-1: -Thyroglobulin is the most abundant protein in the thyroid gland, and the protein backbone for synthesis of T3 and T4 hormones. The most stable form of Tg is a 660 kDa glycoprotein built of two chains (12S forms), 330 kDa each [68].

Detailed explanation-2: -building hormones Thyroglobulin is stored within the gland in follicles as the main component of a substance called the thyroid colloid. This arrangement, which provides a reserve of thyroid hormones, perhaps reflects the frequent scarcity of environmental iodine, particularly on land and in fresh water.

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