The gastrointestinal hormone that stimulates the secretion of hydrochloric acid by parietal cells is:

GASTROINTESTINAL PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	cholecystokinin.
B	The secretin.
C	Pancreozymine.
D	The gastrin.

Explanation:

Detailed explanation-1: -Gastrin is a peptide hormone primarily responsible for enhancing gastric mucosal growth, gastric motility, and secretion of hydrochloric acid (HCl) into the stomach. It is present in G cells of the gastric antrum and duodenum.

Detailed explanation-2: -Gastrin is a hormone that is produced by ‘G’ cells in the lining of the stomach and upper small intestine, and released into the blood circulation. During a meal, gastrin stimulates the stomach to release gastric acid (hydrochloric acid).

Detailed explanation-3: -Gastrin is released from G cells located in the gastric antrum and stimulates enterochromaffin-like (ECL) cells to release histamine, which in turn directly activates acid secretion from the nearby parietal cell.

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