The gastrointestinal hormones have physiological effects that can be elicited at normal concentrations as well as pharmacological effect that require higher than normal concentrations. Which of the following hormone will have the direct physiological affect to stimulate gastric acid secretion?

GASTROINTESTINAL PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	Gastrin
B	Secretin
C	Cholecystokinin (CCK)
D	Motilin

Explanation:

Detailed explanation-1: -Gastrin is a hormone that is produced by ‘G’ cells in the lining of the stomach and upper small intestine, and released into the blood circulation. During a meal, gastrin stimulates the stomach to release gastric acid (hydrochloric acid).

Detailed explanation-2: -Somatostatin and histamine are also produced in the stomach by enterochromaffin-like (ECL) cells, which is an enteroendocrine cell subtype. The small intestines, namely the duodenum and jejunum handle secretion of CCK, secretin, GIP, and motilin.

Detailed explanation-3: -Gastrin is a hormone responsible for hydrochloric acid secretion in the stomach and the motility of the GI tract. Secretin stimulates the secretion of pancreatic bicarbonate to neutralize the acidity of the stomach contents entering the small intestine.

There is 1 question to complete.