MEDICAL PHYSIOLOGY

Detailed explanation-1: -Brunner’s glands are located in the submucosa of the duodenum. They secrete an alkaline fluid containing mucin, which protects the mucosa from the acidic stomach contents entering the duodenum.

Detailed explanation-2: -Brunner’s glands (or duodenal glands) are compound tubular submucosal glands found in that portion of the duodenum which is above the hepatopancreatic sphincter (i.e sphincter of Oddi). It also contains submucosa which creates special glands.

Detailed explanation-3: -Brunner’s gland adenoma, also known as Brunneroma or polypoid hamartoma, is a rare, benign, proliferative lesion arising from the Brunner’s glands of the duodenum, accounting for 10.6% of benign tumors of the duodenum. The time patients are usually asymptomatic and lesions are discovered incidentally.

Detailed explanation-4: -Brunner glands, first described by anatomist Brunner in 1688, are submucosal glands predominantly located in the duodenal bulb and progressively decrease in size and number distally. They function in secreting alkaline viscous mucus protecting the duodenum from acidic gastric chyme.