MEDICAL PHYSIOLOGY

Detailed explanation-1: -Pancreatic juice is secreted into the duodenum through duodenal papillae. Some individuals have also an accessory duct, named accessory pancreatic duct, which may be functional (that is, it also empties the contents of the exocrine pancreas into the duodenum) or non-functional.

Detailed explanation-2: -The pancreatic duct delivers exocrine secretions into the duodenum. The ductal cells secrete fluid and bicarbonate ions, which neutralize acinar cell secretions, as well as the acidic gastric contents entering the duodenum (110).

Detailed explanation-3: -Pancreatic juice is composed of two secretory products critical to proper digestion: digestive enzymes and bicarbonate. The enzymes are synthesized and secreted from the exocrine acinar cells, whereas bicarbonate is secreted from the epithelial cells lining small pancreatic ducts.

Detailed explanation-4: -Pancreatic acinar cells synthesize and secrete almost all the digestive enzymes active in the lumen of the small intestine which are necessary for nutrient digestion. Both synthesis and secretion are highly regulated over both short and long time frames to insure an appropriate supply of digestive enzymes.