PHYSIOLOGY
GASTROINTESTINAL PHYSIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is the main stimulant for HCl secretion and what is the main inhibitor?
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gastrin and somatostatin
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acetylcholine and leptins
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Histamine and somatostatin
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None of the above
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Explanation:
Detailed explanation-1: -Gastrin is a peptide hormone primarily responsible for enhancing gastric mucosal growth, gastric motility, and secretion of hydrochloric acid (HCl) into the stomach.
Detailed explanation-2: -Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility.
Detailed explanation-3: -Somatostatin is present in the gut and acts to decrease acid secretion. The hormone gastrin is released, in a feedback fashion, when the antrum is alkalinized. Most stimuli of acid secretion are blocked by H2-antagonists.
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