Calcium is stored in the ..... and binds to ..... causing tropomyosin to expose myosin binding sites on actic

GENERAL PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Calcium is stored in the ____ and binds to ____ causing tropomyosin to expose myosin binding sites on actic

A	Sarcoplasmic Reticulum/Troponin
B	Sarcoplasmic Reticlum/Myosin heads
C	Endoplasmic Reticulum/Troponin
D	Endoplasmic Reticulum/Myosin heads

Explanation:

Detailed explanation-1: -When calcium floods the cell, troponin binds to it, moving tropomyosin off the myosin binding sites. Opening the myosin binding site on the actin filaments allows the myosin motors to crawl along the actin, resulting in a contraction of the muscle fiber.

Detailed explanation-2: -The calcium ions bind to the troponin, changing the shape of the troponin-tropomyosin complex such that the actin binding sites are uncovered. As soon as myosin binds to actin, the cocked head of myosin releases sliding the actin fiber.

Detailed explanation-3: -Troponin plays a central role in the calcium-regulation of muscle contraction: Troponin is the sole calcium-binding component of thin filaments (actin-tropomyosin-troponin complex) of striated muscles.

There is 1 question to complete.