MEDICAL PHYSIOLOGY

PHYSIOLOGY

GENERAL PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Disease caused by too much cortisol from excessive production of glucose from glycogen and protein, and retention of too much salt; causes fat accumulation in certain areas of the body including the face, abdomen, and back of the neck.
A
Cushing’s syndrome
B
Addison’s disease
C
histamine
D
endocrine system
Explanation: 

Detailed explanation-1: -Cushing’s syndrome results from chronic exposure to excessive circulating levels of glucocorticoids. Cushing’s disease is the most common cause of endogenous hypercortisolism.

Detailed explanation-2: -Cushing’s syndrome is a disorder caused by the body’s exposure to an excess of the hormone cortisol. Cortisol affects all tissues and organs in the body.

Detailed explanation-3: -In Addison’s disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone. Addison’s disease can affect anyone and can be life-threatening. Treatment involves taking hormones to replace those that are missing.

Detailed explanation-4: -The most common cause of Cushing’s syndrome is the long-term, high-dose use of the cortisol-like glucocorticoids. These medicines are used to treat other medical conditions, such as asthma link, rheumatoid arthritis link, and lupus link.

Detailed explanation-5: -With Cushing disease, the pituitary gland releases too much ACTH. ACTH stimulates production and release of cortisol, a stress hormone. Too much ACTH causes the adrenal glands to make too much cortisol. Cortisol is normally released during stressful situations.

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