MEDICAL PHYSIOLOGY

PHYSIOLOGY

GENERAL PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Match the description:Proteins that mark the middle of a sarcommere and connect myosin
A
Tropomyosin
B
Troponin
C
M line
D
Z line
Explanation: 

Detailed explanation-1: -Titin is an extremely large protein (3000 kd), and single titin molecules extend from the M line to the Z disc. These long molecules of titin are thought to act like springs that keep the myosin filaments centered in the sarcomere and maintain the resting tension that allows a muscle to snap back if overextended.

Detailed explanation-2: -The M-lines are mainly containing the ubiquitously expressed proteins, myomesin-1, the muscle isoform of creatine kinase (MM-CK) and the C-terminal part of titin comprising of 10 Ig domains diffused through large unstructured sequences into the entire M-band [15, 17].

Detailed explanation-3: -M line: M line contains the protein called myomesin and it marks the centre of the sarcomere. H zone: it is the area between the M line and Z disc and this zone contains only the myosin.

Detailed explanation-4: -M line-marks the middle of the sarcomere and contains the protein called myomesin. H zone-is the area between the M line and Z disc. The H zone contains only myosin.

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