MEDICAL PHYSIOLOGY

PHYSIOLOGY

GENERAL PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Match the description:spreading of an electric impulse to the deepest myofibrils
A
Sarcolemma
B
sarcoplasmic reticulum
C
T-Tubules
D
Mitochondria
Explanation: 

Detailed explanation-1: -With membranes that contain large concentrations of ion channels, transporters, and pumps, T-tubules permit rapid transmission of the action potential into the cell, and also play an important role in regulating cellular calcium concentration.

Detailed explanation-2: -They allow transmission of the action potential, with its attendant ion shifts, to all parts of the cell, which allows rapid activation of the entire cell. T-tubules are thus a required component of larger cells (Gotoh, 1983).

Detailed explanation-3: -From the T-TUBULES, the impulse passes to the SARCOPLASMIC RETICULUM.

Detailed explanation-4: -The action potential travels down the t-tubules and excites the sarcoplasmic reticulum which releases calcium. Calcium when bound to troponin causes conformational changes in the sarcomere. Consequently, the interaction of thick and thin filaments of the sarcomere leads to muscle contraction.

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