MEDICAL PHYSIOLOGY

PHYSIOLOGY

GENERAL PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The enzyme cholinesterase causes acetylcholine to
A
be secreted from the motor end plate.
B
form cross bridges.
C
bind to actin.
D
decompose.
Explanation: 

Detailed explanation-1: -Acetylcholinesterase (AChE ) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally occurring neurotransmitter, into acetic acid and choline.

Detailed explanation-2: -At least half of the choline used in ACh synthesis is thought to come directly from recycling of released ACh, hydrolyzed to choline by cholinesterase.

Detailed explanation-3: -One important neurotransmitter, acetylcholine, has a specialized enzyme for inactivation right in the synaptic cleft called acetylcholinesterase (AChE. AChE is an enzyme present at all cholinergic synapses which serves to inactivate acetylcholine by hydrolysis.

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