MEDICAL PHYSIOLOGY

PHYSIOLOGY

GENERAL PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The protein that covers the binding site on actin when a muscle is relaxed is called
A
Troponin
B
Myosin
C
Tropomyosin
D
Myofibril
Explanation: 

Detailed explanation-1: -Tropomyosin is a fibrous protein that binds lengthwise along the groove of actin filaments . In striated muscle, each tropomyosin molecule is bound to troponin, which is a complex of three polypeptides: troponin C (Ca2+-binding), troponin I (inhibitory), and troponin T (tropomyosin-binding).

Detailed explanation-2: -Calcium is required by two proteins, troponin and tropomyosin, that regulate muscle contraction by blocking the binding of myosin to filamentous actin. In a resting sarcomere, tropomyosin blocks the binding of myosin to actin.

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