This stage of bone development develops from a fibrous membrane.

GENERAL PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	Intramembranous ossification
B	Endochondral ossification
C	Either A or B
D	None of the above

Explanation:

Detailed explanation-1: -This process involves the direct conversion of mesenchyme to the bone. It begins when neural crest-derived mesenchymal cells differentiate into specialized, bone-forming cells called osteoblasts. Osteoblasts group into clusters and form an ossification center .

Detailed explanation-2: -The stage of intramembranous ossification. The following stages are (a) Mesenchymal cells group into clusters, and ossification centers form. (b) Secreted osteoid traps osteoblasts, which then become osteocytes. (c) Trabecular matrix and periosteum form.

Detailed explanation-3: -Intramembranous ossification = Bone formed by replacing a fibrous membrane and not from cartilage. (ex. Clavicle and skull bones).

Detailed explanation-4: -Answer and Explanation: In both intramembranous and endochondral ossification, the first stage of the development of bone is the penetration of the diaphysis by a nutrient artery (option A).

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