PHYSIOLOGY
GENERAL PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is the structure that blocks the binding sites for Myosin along the Actin fibers?
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Troponin
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Ca
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Tropomyosin
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Sarcolema
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Explanation:
Detailed explanation-1: -In a resting sarcomere, tropomyosin blocks the binding of myosin to actin. In the above analogy of pulling shelves, tropomyosin would get in the way of your hand as it tried to hold the actin rope. For myosin to bind actin, tropomyosin must rotate around the actin filaments to expose the myosin-binding sites.
Detailed explanation-2: -Upon binding calcium, troponin moves tropomyosin away from the myosin-binding sites on actin (bottom), effectively unblocking it.
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