PHYSIOLOGY
GENERAL PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Nicotinic cholinergic receptors
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Muscarinic cholinergic receptors
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Adrenergic receptors
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B and C only
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A, B, and C
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Detailed explanation-1: -Receptor Types and Subtypes Activation of these channels leads to a rapid (msec) response, allowing ions to flow down their electrochemical gradients. Nicotinic cholinergic, GABA-A, and the 5-hydroxytryptamine3 (5HT3) receptor are examples of ligand-gated ion channel sites.
Detailed explanation-2: -The best-studied ligand-gated ion channel is the nicotinic ACh receptor (nAChR), so named because the CNS stimulant, nicotine, also binds to these receptors.
Detailed explanation-3: -Nicotinic Receptors Most of the CNS-type nAChRs are located presynaptically and serve to facilitate or inhibit the release of other mediators, such as glutamate and dopamine. ▼ All nAChRs are pentameric structures that function as ligand-gated ion channels (seeFig. 3.4).
Detailed explanation-4: -The nicotinic acetylcholine (ACh) receptor, at the neuromuscular junction, is a neurotransmitter-gated ion channel that has been fine-tuned through evolution to transduce a chemical signal into an electrical signal with maximum efficiency and speed.