PHYSIOLOGY
GENERAL PHYSIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is (are) directly responsible for the generation of the resting membrane potential?
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Ionic gradients across the plasma membrane
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Permeability of the plasma membrane to various ions
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The Na+/K+ ATPase
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None of the above
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Explanation:
Detailed explanation-1: -(2) Which of the following is (are) directly responsible for the generation of the resting membrane potential? (3) The Na+/K+ ATPase is directly responsible for the establishment of the membrane potential.
Detailed explanation-2: -The resting potential is due primarily to two factors: the high concentration of potassium ions in the intracellular fluid and the high permeability of the cell membrane to potassium ions compared with other ions.
Detailed explanation-3: -The resting potential exists due to the differences in membrane permeabilities for potassium, sodium, calcium, and chloride ions, which in turn result from functional activity of various ion channels, ion transporters, and exchangers.
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