MEDICAL PHYSIOLOGY

PHYSIOLOGY

GENERAL PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which type of bone cells are responsible for dissolving old bone matrix?
A
Osteoblasts
B
Osteoclasts
C
Osteocytes
D
Osteons
Explanation: 

Detailed explanation-1: -Osteoclasts continually break down old bone while osteoblasts continually form new bone.

Detailed explanation-2: -OSTEOCLASTS are large cells that dissolve the bone. They come from the bone marrow and are related to white blood cells. They are formed from two or more cells that fuse together, so the osteoclasts usually have more than one nucleus. They are found on the surface of the bone mineral next to the dissolving bone.

Detailed explanation-3: -Osteoclasts dissolve bone mineral by massive acid secretion and secrete specialized proteinases that degrade the organic matrix, mainly type I collagen, in this acidic milieu.

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