MEDICAL PHYSIOLOGY

PHYSIOLOGY

NEUROTRANSMISSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
For an action potential to occur, enough sodium must flow into the neuron to cause a change in the transmembrane potential from-70mv to-55mv.
A
True
B
False
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -The rate of depolarization, amplitude, and duration of the myocardial action potential all increased in direct proportion to [Na+]o, and no depressant effect on transmembrane action potentials was observed in solutions of high sodium concentration.

Detailed explanation-2: -Once the action potential is triggered, the depolarization (2) of the neuron activates sodium channels, allowing sodium ions to pass through the cell membrane into the cell, resulting in a net positive charge in the neuron relative to the extracellular fluid.

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