PHYSIOLOGY
NEUROTRANSMISSION
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
Local anesthetics work by preventing potassium gates from opening and allowing K+ ions from entering the neuron.
|
|
True
|
|
|
False
|
|
|
Either A or B
|
|
|
None of the above
|
Explanation:
Detailed explanation-1: -Local anesthetics block nerve conduction by preventing the increase in membrane permeability to sodium ions that normally leads to a nerve impulse. Among anesthetics containing tertiary amine groups, the cationic, protonated form appears to be more active than the neutral form.
Detailed explanation-2: -Local anaesthetic agents suppress action potentials in excitable tissues by blocking voltage-gated Na+ channels. In doing so, they inhibit action potentials in nociceptive fibres and so block the transmission of pain impulses.
There is 1 question to complete.