MEDICAL PHYSIOLOGY

Detailed explanation-1: -The arrival of an action potential (a nerve impulse characterized by a rapid change in voltage across a membrane) at the presynaptic terminal causes synaptic vesicles to move toward the presynaptic membrane, where the vesicles then fuse with the membrane and release neurotransmitters.

Detailed explanation-2: -Neurotransmitter is stored inside small sacs called synaptic vesicles, and is released into the synaptic cleft of the synapse when a vesicle fuses with the cell membrane. This process, which is known as exocytosis, can release neurotransmitter in less than a millisecond.

Detailed explanation-3: -The axon terminal of a presynaptic cell, into the synaptic cleft, releases chemicals called neurotransmitters. Neurotransmitters are contained in synaptic vesicles inside the axon terminal.