MEDICAL PHYSIOLOGY

Detailed explanation-1: -Neurotransmitters are stored in small containers (vesicles) located in knoblike structures (terminal buttons) on the axon tips. The axon of the presynaptic neuron does not actually touch the dendrites of the postsynaptic neuron and is separated from them by a space called the synaptic cleft.

Detailed explanation-2: -A small number of vesicles are positioned along the pre-synaptic membrane in places called “active zones.” This is where neurotransmitter release occurs.

Detailed explanation-3: -Neurotransmitter release occurs at synapses, which are the sites of transmission of electric nerve impulses between two neurons or between a neuron and a gland or muscle cell.

Detailed explanation-4: -The neurotransmitters are stored in synaptic vesicles located at the axon terminals, which are released when the synaptic vesicles fuse with the neural membrane following an influx of Ca2+ ions. The neurotransmitters then bind with receptors on the postsynaptic cell to carry out the communication.