MEDICAL PHYSIOLOGY

Detailed explanation-1: -After the neuron has fired, there is a refractory period in which another action potential is not possible. The refractory period generally lasts one millisecond. During this time, the potassium channels reopen and the sodium channels close, gradually returning the neuron to its resting potential.

Detailed explanation-2: -In its wake, the action potential leaves the Na+ channels inactivated and K+ channels activated for a brief time. These transitory changes make it harder for the axon to produce subsequent action potentials during this interval, which is called the refractory period.

Detailed explanation-3: -After an action potential initiates, the cardiac cell is unable to initiate another action potential for some duration of time (which is slightly shorter than the “true” action potential duration). This period of time is referred to as the refractory period, which is 250ms in duration and helps to protect the heart.

Detailed explanation-4: -refractory period. noun. : the brief period immediately following the response especially of a muscle or nerve before it recovers the capacity to make a second response. called also refractory phase.