PHYSIOLOGY
NEUROTRANSMISSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ionic bonding
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diffusion of neurotransmitter across the cleft
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physical contact of axon to dendrite allowing the nerve impulse to continue onward
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diffusion of sodium ions across the cleft
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Detailed explanation-1: -The neurotransmitter will spill into the synaptic cleft, and the vesicle membrane is recovered via endocytosis. Once the neurotransmitter binds to the post-synaptic neuron, it can generally cause one of 2 types of receptors to be activated. It will either activate a ligand-gated ion channel or a G-protein receptor.
Detailed explanation-2: -As a result of the action potential, the chemical transmitter acetylcholine (ACh) is released into the synaptic cleft. ACh diffuses across the synaptic cleft and binds to special receptors on the postsynaptic or the postjunctional membrane.
Detailed explanation-3: -The molecules of neurotransmitter diffuse across the synaptic cleft and bind to receptor proteins on the postsynaptic cell. Activation of postsynaptic receptors leads to the opening or closing of ion channels in the cell membrane.
Detailed explanation-4: -For most of the small-molecule neurotransmitters, specific transporter proteins remove the transmitters (or their metabolites) from the synaptic cleft, ultimately delivering them back to the presynaptic terminal for reuse (see Figure 6.6A).