MEDICAL PHYSIOLOGY

PHYSIOLOGY

NEUROTRANSMISSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
When the charge across the membrane of a neuron is about ____, the charge is called the ____ This is because there are ____
A
-60-70 mV; action potential; more negative ions inside the cell
B
-70-100 mV; action potential; more positive ions inside the cell
C
-60-70mV; resting potential; more positive ions inside the cell
D
-60-70mV; resting potential; more negative ions inside the cell
Explanation: 

Detailed explanation-1: -In most neurons this potential, called the membrane potential, is between −60 and −75 millivolts (mV; or thousandths of a volt; the minus sign indicates that the inner surface is negative). When the inside of the plasma membrane has a negative charge compared to the outside, the neuron is said to be polarized.

Detailed explanation-2: -When the neuronal membrane is at rest, the resting potential is negative due to the accumulation of more sodium ions outside the cell than potassium ions inside the cell.

Detailed explanation-3: -Also the membrane is impermeable to the negatively charged proteins on the inside of the cell. Due to this the inside of the cell is comparatively negative to the outside. Whereas the positive charge gets accumulated outside the axonal membrane of the neuron in the resting phase.

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