MEDICAL PHYSIOLOGY

PHYSIOLOGY

NEUROTRANSMISSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is classified as an antagonist?
A
Cocaine, because it floods the brain with dopamine
B
Mescaline, because it floods the brain with dopamine
C
An amphetamine, because they lead to increased central nervous system activity
D
A tricyclic antidepressant, because they block serotonin and norepinephrine transporters
E
ProzacĀ®, because it blocks the reuptake of serotonin
Explanation: 

Detailed explanation-1: -The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha1B-adrenoceptors. Neuropharmacology.

Detailed explanation-2: -Venlafaxine blocks the neuronal reuptake of serotonin, noradrenaline, and, to a lesser extent, dopamine in the central nervous system.

Detailed explanation-3: -Norpramin (desipramine), Aventyl (nortriptyline), Tofranil (imipramine), and Silenor (doxepin) are among the tricyclic drugs approved to treat depression.

Detailed explanation-4: -Desvenlafaxine (Pristiq) Duloxetine (Cymbalta)-also approved to treat anxiety and certain types of chronic pain. Levomilnacipran (Fetzima) Venlafaxine (Effexor XR)-also approved to treat certain anxiety disorders and panic disorder.

There is 1 question to complete.