MEDICAL PHYSIOLOGY

Detailed explanation-1: -Atherosclerosis is the buildup of fats, cholesterol and other substances in and on the artery walls. This buildup is called plaque. The plaque can cause arteries to narrow, blocking blood flow. The plaque can also burst, leading to a blood clot.

Detailed explanation-2: -Arterial plaque occurs when cholesterol builds up in the inner lining of the artery. This buildup can happen in any artery in the body, from head to toe, and can develop into a condition called atherosclerosis, which can, in turn, lead to coronary artery disease, angina, heart attack or potentially heart failure.

Detailed explanation-3: -Plaques that narrow arteries slowly over time cause angina. Eventually, an area of plaque can break open inside your artery. This causes a blood clots to form on the plaque’s surface. If the clot becomes large enough, it can block blood flow to your heart.