PHYSIOLOGY
RENAL AND ACID BASE PHYSIOLOGY
Question
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During fight or flight, vasoconstriction of the afferent arteriole occurs. What does this cause?
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Decreased blood flow into the glomerulus
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An increase in GFR due to increased back-pressure
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A release of angiotensin II that dilates the afferent arteriole to lower GFR
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Excretion of renin to lower blood pressure
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Explanation:
Detailed explanation-1: -Due to Starling’s law of the heart, increased blood volume will increase blood pressure throughout the body. The increased blood volume with its higher blood pressure will go into the afferent arteriole and into the glomerulus, resulting in increased GFR.
Detailed explanation-2: -Falling blood pressure does the opposite: dilate the afferent arteriole and preserve blood flow to the kidney. Secondly, the renin-angiotensin-aldosterone system acts to preserve GFR. The juxtaglomerular cells in the afferent arteriole release renin in response to decreased stretch.
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