MEDICAL PHYSIOLOGY

PHYSIOLOGY

RENAL AND ACID BASE PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How much of the reabsorption of Na+, K+, and water occurs in the PCT?
A
65%
B
50%
C
80-90%
D
70%
Explanation: 

Detailed explanation-1: -The reabsorption in the proximal tubule is isosmotic. The proximal tubules reabsorb about 65% of water, sodium, potassium and chloride, 100% of glucose, 100% amino acids, and 85-90% of bicarbonate.

Detailed explanation-2: -About 65% of the filtered Na+ is reabsorbed in the PCT. Another 25% is reabsorbed in the thick ascending loop of Henle. Reabsorption of the remaining Na+ occurs in the principal cells of the distal convoluted tubule (DCT) and collecting duct (CD).

Detailed explanation-3: -Almost 100 percent of glucose, amino acids, and vitamins are recovered in the PCT. Bicarbonate (HCO3–) is recovered using the same enzyme, carbonic anhydrase (CA), found in erythrocytes.

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