MEDICAL PHYSIOLOGY

PHYSIOLOGY

RENAL AND ACID BASE PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
If the glomerular filtration rate is too fast:
A
required substances may not be reabsorbed
B
Certain wastes may not be excreted efficiently
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Creatinine is not reabsorbed or secreted, but is exclusively filtered through the kidneys, so its rate of excretion from your bloodstream is directly related to how efficiently your kidneys are filtering.

Detailed explanation-2: -Increasing the GFR increases the filtered load of all solutes, including glucose and amino acids and other solutes that are absorbed by Na+ cotransport. Since these solutes are reabsorbed completely in the proximal tubule, increasing their load increases the amount of Na+ reabsorption proportionately.

Detailed explanation-3: -Low glomerular filtration rate predicts cardiovascular disease, end stage renal disease (a requirement for dialysis or transplantation), and death.

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