PHYSIOLOGY
RENAL AND ACID BASE PHYSIOLOGY
Question
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Proximal Convoluted Tubule
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Loop of Henle
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Distal Conboluted Tubule
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Collecting Ducts
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Detailed explanation-1: -The proximal tubules reabsorb about 65% of water, sodium, potassium and chloride, 100% of glucose, 100% amino acids, and 85-90% of bicarbonate. This reabsorption occurs due to the presence of channels on the basolateral (facing the interstitium) and apical membranes (facing the tubular lumen).
Detailed explanation-2: -Under normal circumstances, up to 180 g/day of glucose is filtered by the renal glomerulus and virtually all of it is subsequently reabsorbed in the proximal convoluted tubule.
Detailed explanation-3: -Glucose and amino acids are reabsorbed by Na+-coupled transport in the proximal tubule (see Fig. 11-10A). A family of transport proteins on the apical surface of the epithelial cell uses the diffusion of Na+ down its electrochemical gradient as the energy source.