PHYSIOLOGY
RENAL AND ACID BASE PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Paracellular
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Transcellular
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Active movement
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Basolateral movement
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Detailed explanation-1: -Reabsorbed substances can be returned to the bloodstream to maintain homeostasis by going between tubule cells (paracellular reabsorption) or by going through individual cells (transcellular reabsorption) on their way to entering a peritubular capillary. Cells in the renal tubule are joined together at tight junctions.
Detailed explanation-2: -Water transport by proximal tubule About 70% of filtered water is reabsorbed along the proximal tubule [26]. This water reabsorption is iso-osmotic and occurs through both transcellular and paracellular pathways.
Detailed explanation-3: -Tubular reabsorption is a passive process whereby drugs are reabsorbed into the systemic circulation from the lumen of the distal tubules. As with enteral absorption, only un-ionized molecules are available for reabsorption.