The juxtaglomerular apparatus is comprised of:

RENAL AND ACID BASE PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	Modified mesangial cells, macula densa cells, and juxtaglomerular cells
B	Lacis cells, modified mesangial cells, and macula densa cells
C	Juxtaglomerular cells and lacis cells
D	Mesangial cells and macula densa cells

Explanation:

Detailed explanation-1: -The juxtaglomerular apparatus consists of the juxtaglomerular cells of the afferent glomerular arteriole, the efferent glomerular arteriole, the extraglomerular mesangial cells, and that small portion of the distal tubule known as the macula densa that is located beside the renal glomerulus.

Detailed explanation-2: -Juxtaglomerular cells or JG cells are modified smooth muscle cells present in the afferent arteriole. These cells are distinguished by their granulated cytoplasm.

Detailed explanation-3: -Juxtaglomerular granular cells are modified smooth muscle cells and are believed to be the source of renin. They are present in the vascular component, being most numerous in the afferent arteriole.

Detailed explanation-4: -The juxtaglomerular apparatus (JGA) controls the rate of the glomerular blood flow depending on various factors such as hydration, blood volume and ion concentration. The JGA includes the macula densa and juxtaglomerular cells.

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