MEDICAL PHYSIOLOGY

PHYSIOLOGY

REPRODUCTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following happen in the uterus?
A
Sperm cells are attacked by the immune system
B
Sperm cells multiply
C
Sperms cells find the egg cell
D
Sperm cells are flushed out of the female reproductive system
Explanation: 

Detailed explanation-1: -The attack by the immune system destroys most of the sperm cells in semen, narrowing the number to just a few hundred that can enter the fallopian tubes. The response is the body’s way to prevent polyspermy, a condition wherein an egg is fertilized by more than one sperm.

Detailed explanation-2: -As Gagneux explains: ‘After crossing the cervix, millions of sperm – a US population worth of sperm – that arrive in the uterus are faced by a barrage of [immune cells] macrophages and neutrophils. ‘

Detailed explanation-3: -Besides, semen also contains immune-suppressive agents secreted by seminal vesicles (accessory structure). Like in the case of men, the sperms do not come in contact with blood once deposited in the vagina. Hence, no immune response against the sperms is caused in the woman.

Detailed explanation-4: -Uterine mucosa is an important tissue barrier whose main function is to offer protection against pathogens and other toxic factors, while maintaining a symbiotic relationship with commensal microbes.

There is 1 question to complete.