MEDICAL PHYSIOLOGY

Detailed explanation-1: -Autocrine signals are produced by signaling cells that can also bind to the ligand that is released, which means the signaling cell and the target cell can be the same or a similar cell. Direct signaling can occur by transferring signaling molecules across gap junctions between neighboring cells.

Detailed explanation-2: -Autocrine signaling means the production and secretion of an extracellular mediator by a cell followed by the binding of that mediator to receptors on the same cell to initiate signal transduction.

Detailed explanation-3: -Paracrine signaling acts on nearby cells, endocrine signaling uses the circulatory system to transport ligands, and autocrine signaling acts on the signaling cell. Signaling via gap junctions involves signaling molecules moving directly between adjacent cells. responses that last only a short amount of time.