MEDICAL PHYSIOLOGY

Detailed explanation-1: -In endocrine signaling, the signaling molecules (hormones) are secreted by specialized endocrine cells and carried through the circulation to act on target cells at distant body sites.

Detailed explanation-2: -Overview of Local Regulator Intercellular signaling falls under the category of local signaling which involves a particular signal molecule to transfer the signal. These small molecules are referred to as local regulators. These regulators are the signal molecules.

Detailed explanation-3: -Local regulators are chemical signals that act over short distances, reaching their target cells by diffusion. ○ For example, immune cells communicate with each other by local regulators called cytokines.

Detailed explanation-4: -Hormones are the chemical signaling molecules produced by the endocrine glands and secreted directly into the bloodstream. They travel through the blood to distant tissues and organs, where they can bind to specific cell sites called receptors.