MEDICAL PHYSIOLOGY

Previous
Next

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
C. elegans is a model organism and was the first eukaryotic organism to have its genome sequence. The free-living nematode is often used in laboratories investigating reproduction, particularly egg laying. There are 16 muscles, 2 types of neurons, and multiple receptors involved in the process of laying eggs in C. elegans and there are mutations in all of these structures for the study of process. One particular mutation that prevents the laying of eggs by the worm is rescued by the neurotransmitter, serotonin. the rescue suggests that the mutation is most likely in which of the following?
A
one of the muscles needed for egg-laying
B
a postsynaptic . neuron involved in egg laying
C
a pre-synaptic neuron involved in egg laying
D
a receptor for serotonin on cells needed for egg laying
Explanation: 

Detailed explanation-1: -Caenorhabditis elegans is a species of nematode worm and is frequently chosen as a model organism to study human diseases.

Detailed explanation-2: -C. elegans grown in large numbers, can be easily screened for effects of novel drugs on complex processes involved in human disease. C. elegans is particularly useful the study of ageing processes because the organism passes through several distinct phases of life which can be observed physiologically and genetically.

Detailed explanation-3: -In 1965, Sydney Brenner settled on Caenorhabditis elegans as a model organism to study animal development and behavior for reasons that are now well known (Brenner, 1973, 1988).

Detailed explanation-4: -The genome sequence of C. elegans is essentially complete. The sequence follows those of viruses, several bacteria, and a yeast (1, 2) and is the first from a multicellular organism.

There is 1 question to complete.
Previous
Next