MEDICAL PHYSIOLOGY

Detailed explanation-1: -Apoptosis is mediated by proteolytic enzymes called caspases, which trigger cell death by cleaving specific proteins in the cytoplasm and nucleus.

Detailed explanation-2: -Apoptosis is the process of programmed cell death. It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand. In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair. Apoptosis also plays a role in preventing cancer.

Detailed explanation-3: -Apoptosis (from Ancient Greek: , romanized: apóptōsis, lit. ‘falling off’) is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death.

Detailed explanation-4: -Neuronal thread protein (AD7c-NTP) AD7c-NTP is a 41kD membrane protein, which induces cell death through apoptosis and impaired mitochondrial function. Moreover levels of proteins involved in apoptosis, such as p53 and Fas/CD95 are increased with AD7c-NTP expression.