MEDICAL PHYSIOLOGY

Detailed explanation-1: -The ATP–creatine phosphate system transfers a high-energy phosphate from creatine phosphate to adenosine diphosphate (ADP) to regenerate ATP. This anaerobic system can provide ATP for approximately 30 seconds for activities such as sprinting and weightlifting.

Detailed explanation-2: -Even before the hard-working muscles run low on ATP, the enzyme creatine kinase (CK) transfers this phosphate group to ADP and converts it back to ATP – but only as long as sufficient levels of phosphocreatine are present.

Detailed explanation-3: -Creatine phosphate provides about the first 15 seconds of ATP at the beginning of muscle contraction. Anaerobic glycolysis produces small amounts of ATP in the absence of oxygen for a short period. Aerobic metabolism utilizes oxygen to produce much more ATP, allowing a muscle to work for longer periods.

Detailed explanation-4: -The phosphagen system (also called the CrP-ATP system) is the quickest way to resynthesize ATP. Creatine phosphate (CrP), which is stored in skeletal muscles, donates a phosphate to ADP to produce ATP.

Detailed explanation-5: -The products of this reaction are ATP and creatine. Creatine phosphate can be obtained from two sources: ingestion of meat and internal production by the liver and kidneys. Creatine and creatinine (fromed from the metabolism of creatine) waste is removed from the body through the kidneys and urinary system.