MEDICAL PHYSIOLOGY

Detailed explanation-1: -Prophase. In this phase the DNA supercoils, chromatin fibres become coiled and condense into chromosomes.

Detailed explanation-2: -During prophase the DNA supercoils, changing from chromatin to distinct chromosomes. Each chromosome consists of two identical sister chromatids, joined together by a centromere. The nuclear membrane disintegrates and the nucleolus disappears.

Detailed explanation-3: -Structure of the nucleus The nucleosomes further condense to form solenoids. The supercoiling of these form the chromosome.

Detailed explanation-4: -Mitosis is division of the nucleus into two genetically identical daughter nuclei. → Chromosomes condense by supercoiling during mitosis.

Detailed explanation-5: -Prophase is the first phase of mitosis, the process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. During prophase, the complex of DNA and proteins contained in the nucleus, known as chromatin, condenses.