MEDICAL PHYSIOLOGY

Detailed explanation-1: -Specifically, the inside of the cell has a negative charge just inside the cell membrane, with a higher concentration of Potassium ions inside the cell; the outside of the cell has a postive charge, with a higher concentration of Sodium ions.

Detailed explanation-2: -The correct answer: For nerve and muscle cells, the inside of the cell is negatively-charged relative to the outside. In the nerve and muscle cells, there are potassium ions inside the cells and sodium ions present outside the cells.

Detailed explanation-3: -In particular, nerve-and muscle-cell membranes are slightly permeable to positive potassium ions, which diffuse outward, leaving a net negative charge in the cell.

Detailed explanation-4: -A neuron at rest is negatively charged: the inside of a cell is approximately 70 millivolts more negative than the outside (−70 mV, note that this number varies by neuron type and by species).

Detailed explanation-5: -Neurons actually have a pretty strong negative charge inside them, in contrast to a positive charge outside. This is due to other molecules called anions. They are negatively charged, but are way too big to leave through any channel. They stay put and give the cell a negative charge inside.