MEDICAL PHYSIOLOGY

Detailed explanation-1: -The Nissl bodies, units of the neuronal ergastoplasm with adjacent ribosomes, represent the light microscopic equivalent of the rough endoplasmic reticulum.

Detailed explanation-2: -The cell body (soma or perikaryon) contains the nucleus and other cell organelles. There are clusters of rough endoplasmic reticulum (not shown in Figure 1) that are called Nissl bodies or are sometimes referred to as chromatophilic substances.

Detailed explanation-3: -Nissl substance is a reticulum of channels within neurons. Its external membranes are studded with rows, loops, and spirals of ribosomes, although some regions are smooth. Ribosomes also lie free in the cytoplasm as polysomal rosettes between cisternae.

Detailed explanation-4: -In cellular neuroscience, Nissl bodies (also called Nissl granules, Nissl substance or tigroid substance) are discrete granular structures in neurons that consist of rough endoplasmic reticulum, a collection of parallel, membrane-bound cisternae studded with ribosomes on the cytosolic surface of the membranes.