MEDICAL PHYSIOLOGY

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Neurotransmitters are released into the synaptic cleft from the presynaptic neuron and travel to a receptor on the post synaptic neuron membrane. Which processes are required for this to happen?
A
Release into synaptic cleft:exocytosis. Travel to post synaptic neuron membrane:diffusion
B
Release into synaptic cleft:active transport. Travel to post synaptic neuron membrane:diffusion
C
Release into synaptic cleft:exocytosis. Travel to post synaptic neuron membrane:active transport
D
Release into synaptic cleft:active transport. Travel to post synaptic neuron membrane:active transport
Explanation: 

Detailed explanation-1: -In a chemical synapse, the action potential causes release of neurotransmitter molecules into the synaptic cleft. Through binding to postsynaptic receptors, the neurotransmitter can cause excitatory or inhibitory postsynaptic potentials by depolarizing or hyperpolarizing, respectively, the postsynaptic membrane.

Detailed explanation-2: -As a result of the action potential, the chemical transmitter acetylcholine (ACh) is released into the synaptic cleft. ACh diffuses across the synaptic cleft and binds to special receptors on the postsynaptic or the postjunctional membrane.

Detailed explanation-3: -When the neurotransmitter has been secreted into the synaptic cleft, it binds to specific receptors on the postsynaptic cell, thereby generating a postsynaptic electrical signal, as described in much more detail in Chapter 7.

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