Refer to the previous question on snake venom. The snake venom mimics neurotransmitters and can attach to receptor proteins on the postsynaptic cell. Therefore, what type of graded potential does the snake venom initiate?

SYNAPTIC PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	EPSP
B	IPSP
C	Action Potential
D	None of the above

Explanation:

Detailed explanation-1: -Neurotoxic snake venoms primarily affect the neuromuscular junction causing a disruption of neurotransmission, resulting in paralysis of the skeletal muscles (Harris 2009; Ranawaka 2013). Snake venom neurotoxins target multiple sites in the neuromuscular junction.

Detailed explanation-2: --neurotoxins are peptide toxins that are abundantly present in the venom of elapid snakes and that competitively inhibit the nicotinic acetylcholine receptor (nAChR) to abolish normal neurotransmission thus leading to paralysis and subsequent respiratory failure.

Detailed explanation-3: -Procoagulant venoms contain components that hasten clot formation. All the procoagu-lants characterized to date are proteinases; they activate a zymogen of specific coagula-tion factors in the coagulation cascade.

Detailed explanation-4: -Phospholipase A, which causes hydrolytic breakdown of membrane phospholipids, is common to many snake venoms. This molecule displays cytotoxic, anticoagulant (prevents activation of clotting factors), and neurotoxic activities.

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