MEDICAL PHYSIOLOGY

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Rigor mortis sets in when there is no calcium to bind to troponin.
A
True
B
False
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Troponin plays a central role in the calcium-regulation of muscle contraction: Troponin is the sole calcium-binding component of thin filaments (actin-tropomyosin-troponin complex) of striated muscles. Thin filaments without troponin support contraction irrespective of calcium concentration.

Detailed explanation-2: -Option A: Rigor Mortis is an irreversible change. Its effects cannot be reversed. Hence, this is the incorrect option.

Detailed explanation-3: -In the rigor hastened by calcium the effects of the extensor muscles mostly prevail; in the rigor following magnesium injection, on the other hand, either the flexor muscles prevail or the muscles become stiff in the original position of the animal at death.

Detailed explanation-4: -When calcium binds to troponin, the troponin changes shape, removing tropomyosin from the binding sites. The sarcoplasmic reticulum stores calcium ions, which it releases when a muscle cell is stimulated; the calcium ions then enable the cross-bridge muscle contraction cycle.

There is 1 question to complete.