MEDICAL PHYSIOLOGY

Detailed explanation-1: -Excitatory synaptic transmission happens when glutamate, the excitatory neurotransmitter, activates receptors on the postsynaptic neuron. Synaptic plasticity is a higher-level process in which the strength of excitatory synapses is altered in response to the pattern of activity at the synapse.

Detailed explanation-2: -Synaptic transmission involves communication between two or more cells. However, synaptic communication is triggered by electrical activity within neurons and involves the movement of electrical charges carried by ions.

Detailed explanation-3: -The release of neurotransmitter from neurons represents one of the pivotal events in synaptic transmission.

Detailed explanation-4: -Neurotransmitters carry chemical signals (“messages”) from one neuron (nerve cell) to the next target cell.

Detailed explanation-5: -Thus, fast synaptic transmission uses neurotransmitters such as ACh, glutamate, GABA, glycine, dopamine (DA) and NE, all of which can be synthesized within the nerve terminal or transported rapidly across the nerve terminal plasma membrane.