True/False:Excitatory potentials cause the neuron to slightly depolarize, bringing it closer to threshold andpromoting an action potential.

SYNAPTIC PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	True
B	False
C	Either A or B
D	None of the above

Explanation:

Detailed explanation-1: -Excitatory postsynaptic potentials (EPSPs) are associated with transmitter-induced increase in Na+ and K+ conductance of the synaptic membrane, resulting in net entry of positive charge carried by Na+ and membrane depolarization.

Detailed explanation-2: -Excitatory postsynaptic potentials (EPSPs) are synaptic inputs thatdepolarize the postsynaptic cell, bringing the membrane potential closer to threshold and closer to firing an action potential.

Detailed explanation-3: -At many other synapses, PSPs actually decrease the probability that the postsynaptic cell will generate an action potential. PSPs are called excitatory (or EPSPs) if they increase the likelihood of a postsynaptic action potential occurring, and inhibitory (or IPSPs) if they decrease this likelihood.

Detailed explanation-4: -Depolarization in a postsynaptic potential is called an excitatory postsynaptic potential (EPSP) because it causes the membrane potential to move toward threshold.

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