True/False:If, under resting conditions, the membrane suddenly becomes more permeable to sodium, the resting membrane potential would become hyperpolarized.

SYNAPTIC PHYSIOLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	True
B	False
C	Either A or B
D	None of the above

Explanation:

Detailed explanation-1: -The correct option is B True A cell membrane is more permeable to potassium ions than sodium ions.

Detailed explanation-2: -This factor brings up an important point: the more permeable the plasma membrane is to a given ion, the more that ion will contribute to the membrane potential (the overall membrane potential will be closer to the equilibrium potential of that ‘dominate’ ion).

Detailed explanation-3: -At normal resting membrane potential, sodium is forced outwards and potassium is carry into the cells (see Fig. 2.4). This requires the sodium-potassium exchange pump, which uses ATP in order to operate. Three intracellular sodium ions will be exchanged for every two extracellular potassium ions.

Detailed explanation-4: -Permeability at Rest When the cell is at rest, some non-gated, or leak, ion channels are actually open. Significantly more potassium channels are open than sodium channels, and this makes the membrane at rest more permeable to potassium than sodium.

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